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(2023) study examined the impact of GLP-1 receptor agonists and sodium-glucose co-transporter-2 inhibitors (SGLT2-Is) on lower limb amputation (LLA) risk using Danish National Health Service registry data from 2013 to 2018
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2.3.2 Gut microbiota and its metabolites modulate GLP-1 secretion Emerging evidence highlights a bidirectional regulatory interplay between the gut microbiota and GLP-1, whereby microbial composition and metabolites exert profound influences on GLP-1 synthesis, secretion, and signaling
Blicher, S
While the treatment with NP4 alone caused a strong production of ROS, the preincubation with NAC and subsequent treatment with NP4 showed a poor ROS generation (Fig
